Title: The signal sequence of the p62 protein of Semliki Forest virus is involved in initiation but not in completing chain translocation Document date: 1990_9_1
ID: rmjv56ia_43
Snippet: In this work we like to use the glycosylation event at Asn,3 of the signal sequence to mark the time point when the latter becomes released into the lumen of the ER. The crucial question then becomes whether it is reasonable to assume that the signal peptide has to be released from the ER membrane before it can become glycosylated. To answer this question we have to consider what is known about the topology of glycosylation as well as the way by .....
Document: In this work we like to use the glycosylation event at Asn,3 of the signal sequence to mark the time point when the latter becomes released into the lumen of the ER. The crucial question then becomes whether it is reasonable to assume that the signal peptide has to be released from the ER membrane before it can become glycosylated. To answer this question we have to consider what is known about the topology of glycosylation as well as the way by which the p62 signal might interact with the ER membrane.
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