Selected article for: "aa tRNA accommodation and rate constant"
Author: Liao, Pei-Yu; Choi, Yong Seok; Dinman, Jonathan D.; Lee, Kelvin H.
Title: The many paths to frameshifting: kinetic modelling and analysis of the effects of different elongation steps on programmed –1 ribosomal frameshifting
  • Document date: 2010_9_7
    • ID: wwq0sd2r_10
    Snippet: In the second pathway, the downstream stimulatory structure induces ribosome pausing and promotes À1 PRF during aa-tRNA accommodation. Pathway II suggests that simultaneous slippage of P-and A-site tRNAs occurs during accommodation and/or before peptidyltransfer. In Figure 2 , the process from P 0 A 0 to P 02 A 02 with the rate constant k pas2 describes the slippage in Pathway II. P 02 A 02 then proceeds through peptidyltransfer to generate FS z.....
    Document: In the second pathway, the downstream stimulatory structure induces ribosome pausing and promotes À1 PRF during aa-tRNA accommodation. Pathway II suggests that simultaneous slippage of P-and A-site tRNAs occurs during accommodation and/or before peptidyltransfer. In Figure 2 , the process from P 0 A 0 to P 02 A 02 with the rate constant k pas2 describes the slippage in Pathway II. P 02 A 02 then proceeds through peptidyltransfer to generate FS z .

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