Author: Josset, Laurence; Zeng, Hui; Kelly, Sara M.; Tumpey, Terrence M.; Katze, Michael G.
Title: Transcriptomic Characterization of the Novel Avian-Origin Influenza A (H7N9) Virus: Specific Host Response and Responses Intermediate between Avian (H5N1 and H7N7) and Human (H3N2) Viruses and Implications for Treatment Options Document date: 2014_2_4
ID: uz0m1o0q_29
Snippet: Functional enrichment and upstream regulator analysis. Functional analysis of statistically significant gene expression changes was performed using the Ingenuity Pathways Knowledge Base (IPA; Ingenuity Systems). For all gene set enrichment analyses, a right-tailed Fisher exact test was used to calculate a P value determining the probability that each biological function assigned to that data set was due to chance alone. All enrichment scores were.....
Document: Functional enrichment and upstream regulator analysis. Functional analysis of statistically significant gene expression changes was performed using the Ingenuity Pathways Knowledge Base (IPA; Ingenuity Systems). For all gene set enrichment analyses, a right-tailed Fisher exact test was used to calculate a P value determining the probability that each biological function assigned to that data set was due to chance alone. All enrichment scores were calculated in IPA using the probes that passed our QC filter as the background data set.
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