Author: Teoh, Kim-Tat; Siu, Yu-Lam; Chan, Wing-Lim; Schlüter, Marc A.; Liu, Chia-Jen; Peiris, J. S. Malik; Bruzzone, Roberto; Margolis, Benjamin; Nal, Béatrice
Title: The SARS Coronavirus E Protein Interacts with PALS1 and Alters Tight Junction Formation and Epithelial Morphogenesis Document date: 2010_11_15
ID: ufw13pjx_48
Snippet: To further document the subcellular localization of PALS1 in SARS-CoV–infected cells, specific antibodies against Calnexin, an endoplasmic reticulum (ER)-resident protein and Golgin-97, a trans-Golgi marker, were used in combination with anti-PALS1 antibodies (Figure 3B, panels a and b). Our data show that PALS1 does not accumulate in the ER and is present in the Golgi compartment......
Document: To further document the subcellular localization of PALS1 in SARS-CoV–infected cells, specific antibodies against Calnexin, an endoplasmic reticulum (ER)-resident protein and Golgin-97, a trans-Golgi marker, were used in combination with anti-PALS1 antibodies (Figure 3B, panels a and b). Our data show that PALS1 does not accumulate in the ER and is present in the Golgi compartment.
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