Author: Dawson, Patrick; Malik, Mamunur Rahman; Parvez, Faruque; Morse, Stephen S.
Title: What Have We Learned About Middle East Respiratory Syndrome Coronavirus Emergence in Humans? A Systematic Literature Review Document date: 2019_3_1
ID: yb54i1ne_16
Snippet: Particular attention has understandably focused on the S (spike) surface protein, which confers receptor specificity (Qian et al. 2013 ) and is considered the major determinant of coronavirus host range (Graham and Baric 2010, Hulswit et al. 2016) . The main route of entry for MERS-CoV is dipeptidyl peptidase 4 (DPP4, also known as CD26) on the host cell surface , which is utilized by the receptorbinding domain of the MERS-CoV spike protein (Chen.....
Document: Particular attention has understandably focused on the S (spike) surface protein, which confers receptor specificity (Qian et al. 2013 ) and is considered the major determinant of coronavirus host range (Graham and Baric 2010, Hulswit et al. 2016) . The main route of entry for MERS-CoV is dipeptidyl peptidase 4 (DPP4, also known as CD26) on the host cell surface , which is utilized by the receptorbinding domain of the MERS-CoV spike protein (Chen et al. 2013 .
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