Author: Wei Zhen; Ryhana Manji; Elizabeth Smith; Gregory J Berry
Title: Comparison of Four Molecular In Vitro Diagnostic Assays for the Detection of SARS-CoV-2 in Nasopharyngeal Specimens Document date: 2020_4_22
ID: 2bf3xzni_23
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.17.20069864 doi: medRxiv preprint Workflow evaluation. Hands-on time (HOT), run time, and overall turnaround time (TAT) to results were 217 assessed for all pre-analytical, analytical, and post-analytical steps for all four platforms. Results of the 218 workflow assessment are shown in Table 5 . The HOT ranged between all platforms. The l.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.17.20069864 doi: medRxiv preprint Workflow evaluation. Hands-on time (HOT), run time, and overall turnaround time (TAT) to results were 217 assessed for all pre-analytical, analytical, and post-analytical steps for all four platforms. Results of the 218 workflow assessment are shown in Table 5 . The HOT ranged between all platforms. The longest hands-219 on time was the Hologic assay at ~2 hours followed by the modified CDC assay with ~1 hour and 30 220 minutes. Very comparable HOT was found for DiaSorin Molecular and GenMark with a range of 16 221 minutes and 12 minutes, respectively. The run time averaged 90 minutes for modified CDC, DiaSorin 222 Molecular, and GenMark. Hologic was the exception with 4 hours with 35 mins of run time ( Table 5) . 223
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