Selected article for: "convalescent plasma transfusion and plasma transfusion"
Author: van Griensven, Johan; De Weiggheleire, Anja; Delamou, Alexandre; Smith, Peter G.; Edwards, Tansy; Vandekerckhove, Philippe; Bah, Elhadj Ibrahima; Colebunders, Robert; Herve, Isola; Lazaygues, Catherine; Haba, Nyankoye; Lynen, Lutgarde
Title: The Use of Ebola Convalescent Plasma to Treat Ebola Virus Disease in Resource-Constrained Settings: A Perspective From the Field
  • Document date: 2016_1_1
    • ID: riw5xs3j_1
    Snippet: Convalescent blood or plasma transfusion has been used in clinical settings for >100 years [1] . Until the advent of antibiotic therapy, it was widely used for a range of bacterial and viral diseases. A recent meta-analysis suggests that it could have contributed to an absolute reduction in mortality of around 20% during the 1918 influenza epidemic [2] . At present, hyperimmune globulin, manufactured from convalescent donors' plasma, is still emp.....
    Document: Convalescent blood or plasma transfusion has been used in clinical settings for >100 years [1] . Until the advent of antibiotic therapy, it was widely used for a range of bacterial and viral diseases. A recent meta-analysis suggests that it could have contributed to an absolute reduction in mortality of around 20% during the 1918 influenza epidemic [2] . At present, hyperimmune globulin, manufactured from convalescent donors' plasma, is still employed as prophylaxis or treatment for certain infectious diseases (eg, measles, diphtheria, polio, hepatitis A and B) [3] . Passive antibody therapy is not a new intervention but a widely tested, safe, and proven prophylactic and therapeutic intervention.

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