Author: Raison, C L; Miller, A H
Title: The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D) Document date: 2012_1_31
ID: twgs7akl_24
Snippet: Proinflammatory cytokines induce a behavioral state of conservation-withdrawal, 351 characterized by depressed mood, anhedonia, psychomotor retardation, fatigue, social avoidance and anorexia. 163, 252, 352, 353 This state is an integral component of depressive disorders and has been widely considered to develop in the context of infection and/or tissue injury as a means of marshalling limited metabolic resources for the expensive tasks of immune.....
Document: Proinflammatory cytokines induce a behavioral state of conservation-withdrawal, 351 characterized by depressed mood, anhedonia, psychomotor retardation, fatigue, social avoidance and anorexia. 163, 252, 352, 353 This state is an integral component of depressive disorders and has been widely considered to develop in the context of infection and/or tissue injury as a means of marshalling limited metabolic resources for the expensive tasks of immune activation, fever generation and tissue repair. 311 In addition to energy Table 3 Inflammation and infectious outcomes in industrialized societies
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