Author: Song, Joon Young; Cheong, Hee Jin; Choi, Min Joo; Jeon, Ji Ho; Kang, Seong Hee; Jeong, Eun Ju; Yoon, Jin Gu; Lee, Saem Na; Kim, Sung Ran; Noh, Ji Yun; Kim, Woo Joo
Title: Viral Shedding and Environmental Cleaning in Middle East Respiratory Syndrome Coronavirus Infection Document date: 2015_12_30
ID: x11dr866_1
Snippet: Since the first report of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in September 2012, more than 1,300 cases have been laboratory-confirmed worldwide as of July 10th, 2015. However, sustained human-to-human transmission is unlikely to occur in community setting. R 0 for MERS-CoV is generally estimated to be less than 0.7 [1] . In comparison, hospital-associated outbreaks were reported in Middle East Asia [2, 3] . Similarly.....
Document: Since the first report of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in September 2012, more than 1,300 cases have been laboratory-confirmed worldwide as of July 10th, 2015. However, sustained human-to-human transmission is unlikely to occur in community setting. R 0 for MERS-CoV is generally estimated to be less than 0.7 [1] . In comparison, hospital-associated outbreaks were reported in Middle East Asia [2, 3] . Similarly in the Republic of Korea (ROK), most MERS cases were linked to hospitals [4] . It is still unclear why MERS-CoV spreads easily among patients in hospital setting. Healthcare worker-mediated transmission and environmental contamination might play an important role in the development of hospital-associated outbreak. To better understand the hospital-based transmission, we investigated the duration of viral shedding and environmental contamination in two cases with laboratory-confirmed MERS-CoV infection. Viral loads were presumed through the threshold cycle (Ct) values from real-time RT-PCR.
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