Author: Yishan Zheng; Zhen Huang; Guoping Ying; Xia Zhang; Wei Ye; Zhiliang Hu; Chunmei Hu; Hongxia Wei; Yi Zeng; Yun Chi; Cong Cheng; Feishen Lin; Hu Lu; Lingyan Xiao; Yan Song; Chunming Wang; Yongxiang Yi; Lei Dong
Title: Comparative study of the lymphocyte change between COVID-19 and non-COVID-19 pneumonia cases suggesting uncontrolled inflammation might not be the main reason of tissue injury Document date: 2020_2_23
ID: 5ge7ozpd_32
Snippet: Current treatments do not suggest using specific drugs to improve the activity of immune systems, such as the GM-CSF or other immune stimuli, in fearing of the exaggeration of inflammatory reactions and cytokine storm. 19 Taken together, our analysis in the present study, based on clinical data, demonstrate significant differences between pneumonia caused and not caused by 2019-nCoVespecially including the lymphocytopenia. Our results further sug.....
Document: Current treatments do not suggest using specific drugs to improve the activity of immune systems, such as the GM-CSF or other immune stimuli, in fearing of the exaggeration of inflammatory reactions and cytokine storm. 19 Taken together, our analysis in the present study, based on clinical data, demonstrate significant differences between pneumonia caused and not caused by 2019-nCoVespecially including the lymphocytopenia. Our results further suggest that the tissue damage to COVID-19 patients might be mainly due to virus infection itself rather than uncontrolled inflammatory reactions. These findings are valuable for the development of more efficient treatments.
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