Selected article for: "challenge animal and MERS cov"
Author: Dawson, Patrick; Malik, Mamunur Rahman; Parvez, Faruque; Morse, Stephen S.
Title: What Have We Learned About Middle East Respiratory Syndrome Coronavirus Emergence in Humans? A Systematic Literature Review
  • Document date: 2019_3_1
    • ID: yb54i1ne_57
    Snippet: There are special challenges to developing a MERS vaccine. The sporadic nature of human MERS-CoV infection and the difficulty of identifying suitable animal models for challenge studies make controlled trials difficult. Disease in camels usually appears mild (Adney et al. 2014) , reducing the economic incentive for immunization. A camel vaccine could also be given in combination with a required vaccine, e.g., rabies, as suggested by Wirblich et a.....
    Document: There are special challenges to developing a MERS vaccine. The sporadic nature of human MERS-CoV infection and the difficulty of identifying suitable animal models for challenge studies make controlled trials difficult. Disease in camels usually appears mild (Adney et al. 2014) , reducing the economic incentive for immunization. A camel vaccine could also be given in combination with a required vaccine, e.g., rabies, as suggested by Wirblich et al. (2017) , or camelpox, as suggested by Haagmans et al. (2016) .

    Search related documents:
    Co phrase search for related documents
    • animal model and controlled trial: 1, 2
    • animal model and human MERS cov infection: 1, 2, 3, 4, 5, 6
    • animal model and MERS cov: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • animal model and MERS cov infection: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
    • animal model and MERS vaccine: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • animal model and required vaccine: 1
    • camel disease and MERS cov: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • camel disease and MERS cov infection: 1, 2, 3, 4
    • camel disease and MERS vaccine: 1, 2
    • camel disease and MERS vaccine develop: 1
    • camel vaccine and MERS cov: 1, 2, 3, 4, 5, 6, 7
    • camel vaccine and MERS cov infection: 1, 2
    • camel vaccine and MERS vaccine: 1, 2, 3, 4, 5
    • challenge study and controlled trial: 1, 2, 3, 4
    • challenge study and MERS cov: 1, 2, 3, 4, 5
    • challenge study and MERS cov infection: 1, 2, 3
    • challenge study and required vaccine: 1
    • combination give and controlled trial: 1
    • controlled trial and required vaccine: 1