Selected article for: "blood mononuclear and peripheral blood mononuclear cell"
Author: Kim, Chang-Keun; Callaway, Zak; Gern, James E.
Title: Viral Infections and Associated Factors That Promote Acute Exacerbations of Asthma
  • Document date: 2017_10_13
    • ID: u4rtnyj7_19
    Snippet: RV infection and allergic sensitization synergistically increase the risk of wheezing illnesses. 56 Atopic asthma can be associated with reduced virus-induced IFN responses, decreased viral clearance 57 and increased viral shedding. 58 In some studies, atopic asthmatics vs non-atopic controls have reduced peripheral blood mononuclear cell (PBMC) IFN responses. 59 Furthermore, some studies have found that bronchial epithelial cells of atopic asthm.....
    Document: RV infection and allergic sensitization synergistically increase the risk of wheezing illnesses. 56 Atopic asthma can be associated with reduced virus-induced IFN responses, decreased viral clearance 57 and increased viral shedding. 58 In some studies, atopic asthmatics vs non-atopic controls have reduced peripheral blood mononuclear cell (PBMC) IFN responses. 59 Furthermore, some studies have found that bronchial epithelial cells of atopic asthmatics permit increased RV replication, enhanced cell lysis, and deficient release of IFN-β. 60 Studies of children with allergic asthma treated with omalizumab indicate that neutralizing immunoglobulin E (IgE)-mediated inflammation

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