Author: Song, Joon Young; Cheong, Hee Jin; Choi, Min Joo; Jeon, Ji Ho; Kang, Seong Hee; Jeong, Eun Ju; Yoon, Jin Gu; Lee, Saem Na; Kim, Sung Ran; Noh, Ji Yun; Kim, Woo Joo
Title: Viral Shedding and Environmental Cleaning in Middle East Respiratory Syndrome Coronavirus Infection Document date: 2015_12_30
ID: x11dr866_8
Snippet: In the present study, both cases presented cough, sputum and diarrhea. Particularly in case 1, diarrhea was the first manifestation and persisted for 10 days after hospitalization. As reported previously, MERS-CoV shedding was detected from both sputum and stool samples [8] . Depending on the patient's condition, the environment may have a chance to be contaminated by both respiratory and gastrointestinal secretions. Viral loads of human coronavi.....
Document: In the present study, both cases presented cough, sputum and diarrhea. Particularly in case 1, diarrhea was the first manifestation and persisted for 10 days after hospitalization. As reported previously, MERS-CoV shedding was detected from both sputum and stool samples [8] . Depending on the patient's condition, the environment may have a chance to be contaminated by both respiratory and gastrointestinal secretions. Viral loads of human coronavirus (hCoV) peak at different time points during the progression of disease: for non-SARS-CoV (e.g. hCoV-NL63), peak viral loads are detected around day 1-2 after onset of disease, while SARS-CoV viral loads gradually increase until day 10 [9] . Although data on viral kinetics is insufficient, higher respiratory tract viral loads were suggested in MERS-CoV infection compared to SARS-CoV during the first week of illness [1] . Strict contact/droplet precaution and environmental cleaning would be required to prevent intra-hospital spread of MERS-CoV infection.
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