Author: Dawson, Patrick; Malik, Mamunur Rahman; Parvez, Faruque; Morse, Stephen S.
Title: What Have We Learned About Middle East Respiratory Syndrome Coronavirus Emergence in Humans? A Systematic Literature Review Document date: 2019_3_1
ID: yb54i1ne_40
Snippet: Persistence of antibody generally seems to follow a similar pattern. Detectable neutralizing antibody titers ( ‡20) have been reported in some patients up to 34 months (Payne et al. 2016 ). However, results varied considerably even within this group, and most reports indicate that duration of antibody response, as well as its magnitude, seemed most closely correlated with disease severity and that antibodies could be low or even absent in mild .....
Document: Persistence of antibody generally seems to follow a similar pattern. Detectable neutralizing antibody titers ( ‡20) have been reported in some patients up to 34 months (Payne et al. 2016 ). However, results varied considerably even within this group, and most reports indicate that duration of antibody response, as well as its magnitude, seemed most closely correlated with disease severity and that antibodies could be low or even absent in mild or asymptomatic infection ). These reports of low or waning antibody titers, especially in asymptomatic or mildly symptomatic individuals, may make serology problematic as a marker of population prevalence.
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