Author: Thornton, Hannah V; Hay, Alastair D; Redmond, Niamh M; Turnbull, Sophie L; Christensen, Hannah; Peters, Tim J; Leeming, John P; Lovering, Andrew; Vipond, Barry; Muir, Peter; Blair, Peter S
Title: Throat swabs in children with respiratory tract infection: associations with clinical presentation and potential targets for point-of-care testing Document date: 2017_2_18
ID: r3fzwy00_39
Snippet: Our analysis found no evidence that clinical presentation is associated with the detection of one or more RTI-related bacteria, and little evidence that clinical presentation is associated with the detection of one or more RTI-related viruses, in children presenting to primary care with RTI. Clinical presentation was not sufficiently sensitive or specific to predict detection of individual microbes from the throat, with the exception of RSV, whic.....
Document: Our analysis found no evidence that clinical presentation is associated with the detection of one or more RTI-related bacteria, and little evidence that clinical presentation is associated with the detection of one or more RTI-related viruses, in children presenting to primary care with RTI. Clinical presentation was not sufficiently sensitive or specific to predict detection of individual microbes from the throat, with the exception of RSV, which showed reasonable association with four symptoms and signs (blocked nose, high temperature, productive cough and shortness of breath) and two temporal factors (age <2 years and recruitment in the months of October-March).
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