Author: Thornton, Hannah V; Hay, Alastair D; Redmond, Niamh M; Turnbull, Sophie L; Christensen, Hannah; Peters, Tim J; Leeming, John P; Lovering, Andrew; Vipond, Barry; Muir, Peter; Blair, Peter S
Title: Throat swabs in children with respiratory tract infection: associations with clinical presentation and potential targets for point-of-care testing Document date: 2017_2_18
ID: r3fzwy00_50
Snippet: A 2007 Health Technology Assessment report discusses the use of validation in evaluating a diagnostic test in the absence of 'an unproblematic and equivocal reference standard'. (18) The associations demonstrated here between clinical presentation and upper respiratory tract microbes provide little evidence to suggest that some microbes detected from the upper respiratory tract using throat swabs may be aetiologically related to acute RTI and cou.....
Document: A 2007 Health Technology Assessment report discusses the use of validation in evaluating a diagnostic test in the absence of 'an unproblematic and equivocal reference standard'. (18) The associations demonstrated here between clinical presentation and upper respiratory tract microbes provide little evidence to suggest that some microbes detected from the upper respiratory tract using throat swabs may be aetiologically related to acute RTI and cough. This evidence in isolation is not sufficient, but should be considered alongside evidence from future studies (18) .
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