Author: Dawson, Patrick; Malik, Mamunur Rahman; Parvez, Faruque; Morse, Stephen S.
Title: What Have We Learned About Middle East Respiratory Syndrome Coronavirus Emergence in Humans? A Systematic Literature Review Document date: 2019_3_1
ID: yb54i1ne_33
Snippet: Disease outcomes differed by age and comorbidities (Assiri et al. 2013a , Khalid et al. 2014 , Alsahafi and Cheng 2016 . Most cases in Saudi Arabia have occurred among men, ages 45 or older, and those living in areas of lower relative humidity and high temperature (Alghamdi et al. 2014) . A review of 939 cases in Saudi Arabia found that CFR increases with age, from 12.5% among those 19 years or younger to 86.2% among those 80 years or older (Alsa.....
Document: Disease outcomes differed by age and comorbidities (Assiri et al. 2013a , Khalid et al. 2014 , Alsahafi and Cheng 2016 . Most cases in Saudi Arabia have occurred among men, ages 45 or older, and those living in areas of lower relative humidity and high temperature (Alghamdi et al. 2014) . A review of 939 cases in Saudi Arabia found that CFR increases with age, from 12.5% among those 19 years or younger to 86.2% among those 80 years or older (Alsahafi and Cheng 2016) . Mortality was more frequent and rapid in individuals with comorbidities such as diabetes, chronic renal disease, and, in one study, higher body mass index (Assiri et al. 2013a , Khalid et al. 2014 , Alsahafi and Cheng 2016 . More severe disease has been associated with higher viral load (Feikin et al. 2015) .
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