Author: Dawson, Patrick; Malik, Mamunur Rahman; Parvez, Faruque; Morse, Stephen S.
Title: What Have We Learned About Middle East Respiratory Syndrome Coronavirus Emergence in Humans? A Systematic Literature Review Document date: 2019_3_1
ID: yb54i1ne_61
Snippet: The source of infection for most primary cases (the first known human case in a potential or putative chain of transmission) remains unknown. Baseline incidence and prevalence are unknown as only clinical cases or those found through contact tracing are generally identified. The few population-based studies that have been done appear to show low prevalence in the general population. A serological study of 10,009 individuals in Saudi Arabia found .....
Document: The source of infection for most primary cases (the first known human case in a potential or putative chain of transmission) remains unknown. Baseline incidence and prevalence are unknown as only clinical cases or those found through contact tracing are generally identified. The few population-based studies that have been done appear to show low prevalence in the general population. A serological study of 10,009 individuals in Saudi Arabia found 15 seropositive for MERS-CoV, 7 of whom were occupationally camelexposed (shepherds and slaughterhouse workers) , although the occupational samples were collected for a separate study and therefore may not be representative. In another study of 57,363 persons with suspected MERS-CoV infection tested by Saudi Arabia from April 2015 to February 2016, only 384 (0.7%) tested positive (Bin Saeed et al. 2017) .
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