Author: Chan, Jasper Fuk-Woo; Zhang, Anna Jinxia; Chan, Chris Chung-Sing; Yip, Cyril Chik-Yan; Mak, Winger Wing-Nga; Zhu, Houshun; Poon, Vincent Kwok-Man; Tee, Kah-Meng; Zhu, Zheng; Cai, Jian-Piao; Tsang, Jessica Oi-Ling; Chik, Kenn Ka-Heng; Yin, Feifei; Chan, Kwok-Hung; Kok, Kin-Hang; Jin, Dong-Yan; Au-Yeung, Rex Kwok-Him; Yuen, Kwok-Yung
Title: Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons Document date: 2016_11_12
ID: v4r5d26a_20
Snippet: Abbreviations: dpi, days post-inoculation; F, female; IFN, interferon; ip, intraperitoneal; M, male; sc, subcutaneous. a 6-8 week-old BALB/c mice were used in all the groups. b The preparations of pegylated IFN-α2b and IFN-β1b used in this study were PegIntron (Merck & Co., Inc., Whitehouse Station, NJ, USA) and Betaferon (Bayer Schering Pharma AG, Berlin, Germany), respectively. c The mice in group 1 were euthanized at 12 dpi as they had ≥10.....
Document: Abbreviations: dpi, days post-inoculation; F, female; IFN, interferon; ip, intraperitoneal; M, male; sc, subcutaneous. a 6-8 week-old BALB/c mice were used in all the groups. b The preparations of pegylated IFN-α2b and IFN-β1b used in this study were PegIntron (Merck & Co., Inc., Whitehouse Station, NJ, USA) and Betaferon (Bayer Schering Pharma AG, Berlin, Germany), respectively. c The mice in group 1 were euthanized at 12 dpi as they had ≥10% weight loss and ≥1 clinical symptom.
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