Author: Michael Jay Corley; Christopher Sugai; Michael Schotsaert; Robert E. Schwartz; Lishomwa C Ndhlovu
Title: Comparative in vitro transcriptomic analyses of COVID-19 candidate therapy hydroxychloroquine suggest limited immunomodulatory evidence of SARS-CoV-2 host response genes. Document date: 2020_4_14
ID: 30x26ip7_47
Snippet: COVID-19 and uninfected control gene expression data from bulk PBMC, alveolar lavage, and postmortem lung biopsies were analyzed using the CIBERSORT [25] analytical tool to provide an estimate of the abundances of immune cell types in the mixed cell/tissue population. The existing 22 cell type immune signature matrix was used for reference cell types for analysis......
Document: COVID-19 and uninfected control gene expression data from bulk PBMC, alveolar lavage, and postmortem lung biopsies were analyzed using the CIBERSORT [25] analytical tool to provide an estimate of the abundances of immune cell types in the mixed cell/tissue population. The existing 22 cell type immune signature matrix was used for reference cell types for analysis.
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