Selected article for: "exposure risk and high exposure risk"

Author: Wardrop, K.J.; Birkenheuer, A.; Blais, M.C.; Callan, M.B.; Kohn, B.; Lappin, M.R.; Sykes, J.
Title: Update on Canine and Feline Blood Donor Screening for Blood-Borne Pathogens
  • Document date: 2016_1_25
  • ID: rb7ex6vw_12
    Snippet: Seronegative and PCR negative, especially in high risk dogs PCR negative High risk dogs include greyhounds and those with a history of exposure to Rhipicephalus ticks. (continued) (continued) included in the text and in Tables 1 and 2. These recommendations were made using available evidence from human and veterinary medical literature, and, where evidence was lacking, the combined opinions and clinical experiences of the panel members were used .....
    Document: Seronegative and PCR negative, especially in high risk dogs PCR negative High risk dogs include greyhounds and those with a history of exposure to Rhipicephalus ticks. (continued) (continued) included in the text and in Tables 1 and 2. These recommendations were made using available evidence from human and veterinary medical literature, and, where evidence was lacking, the combined opinions and clinical experiences of the panel members were used to develop recommendations. The goal of the optimal standards is to minimize risk to the best of our ability by application of currently available diagnostic tests. However, the panel acknowledged that application of all diagnostic tests might not be relevant for all geographic locations and donor backgrounds (eg, breed, environment) and some diagnostic tests have limited availability or could be cost prohibitive for some programs. Therefore, the minimal standards were developed taking into account these factors. In some cases, this approach unfortunately could result in movement of infected animals into the donor pool. The panel also discussed alternative acceptable strategies for geographic regions where the prevalence of infection may be high and identification of suitable donors is difficult as well as screening of potential donors when blood is required in an emergency situation and time does not permit thorough screening before donation. An apparently healthy donor may be acceptable in that situation given the low risk of transmission of infection when weighed alongside a high risk of death of the recipient in the absence of blood product transfusion. However, preemptive identification and screening of healthy blood donors remains an important strategy of safe blood banking.

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