Author: Christensen, Maria H; Paludan, Søren R
Title: Viral evasion of DNA-stimulated innate immune responses Document date: 2016_3_14
ID: pvdlox4j_11
Snippet: Inhibition of DNA-activated signaling pathways Herpesvirus genomes are recognized by several DNA receptors, which share the feature that they utilize the adaptor protein STING for downstream signaling. 27, 34 Consequently, to ensure a broad inhibition of Herpesvirus-induced type I IFN, targeting of STING as well as the STING interaction partner, TBK1 would be an efficient means to block early antiviral defense......
Document: Inhibition of DNA-activated signaling pathways Herpesvirus genomes are recognized by several DNA receptors, which share the feature that they utilize the adaptor protein STING for downstream signaling. 27, 34 Consequently, to ensure a broad inhibition of Herpesvirus-induced type I IFN, targeting of STING as well as the STING interaction partner, TBK1 would be an efficient means to block early antiviral defense.
Search related documents:
Co phrase search for related documents- adaptor protein and DNA receptor: 1, 2
- adaptor protein and downstream signaling: 1, 2, 3, 4
- adaptor protein and signaling pathway: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- adaptor protein and STING interaction: 1, 2
- antiviral defense and downstream signaling: 1, 2, 3, 4
- antiviral defense and early antiviral defense: 1, 2, 3, 4, 5, 6
- antiviral defense and signaling pathway: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- broad inhibition and DNA receptor: 1
- broad inhibition and downstream signaling: 1
- broad inhibition and signaling pathway: 1
- DNA activate and STING interaction: 1
- DNA receptor and signaling pathway: 1, 2, 3, 4, 5
- DNA receptor and STING interaction: 1
- downstream signaling and signaling pathway: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- downstream signaling and STING interaction: 1
Co phrase search for related documents, hyperlinks ordered by date