Author: Shuaiyao Lu; Yuan Zhao; Wenhai Yu; Yun Yang; Jiahong Gao; Junbin Wang; Dexuan Kuang; Mengli Yang; Jing Yang; Chunxia Ma; Jingwen Xu; Haiyan Li; Siwen Zhao; Jingmei Li; Haixuan Wang; Haiting Long; Jingxian Zhou; Fangyu Luo; Kaiyun Ding; Daoju Wu; Yong Zhang; Yingliang Dong; Yuqin Liu; Yingqiu Zheng; Xiaochen Lin; Li Jiao; Huanying Zheng; Qing Dai; Qiangmin Sun; Yunzhang Hu; Changwen Ke; Hongqi Liu; Xiaozhong Peng
Title: Comparison of SARS-CoV-2 infections among 3 species of non-human primates Document date: 2020_4_12
ID: czh3zfb3_8
Snippet: fascicularis, lower levels of viral RNA were detected in swab samples from C. jacchus during two weeks post viral inoculation ( Figure 3B ). Virus shedding in feces from 8 out of 18 old world monkeys started on 6 dpi. Notably, higher levels of viral RNA were detected in feces from SXH6, HHH6, HHH11 and HHH12, from which anal swabs also gave correspondingly higher number of viral RNA. In peripheral blood, 8/18 old world monkeys and 6/6 new world m.....
Document: fascicularis, lower levels of viral RNA were detected in swab samples from C. jacchus during two weeks post viral inoculation ( Figure 3B ). Virus shedding in feces from 8 out of 18 old world monkeys started on 6 dpi. Notably, higher levels of viral RNA were detected in feces from SXH6, HHH6, HHH11 and HHH12, from which anal swabs also gave correspondingly higher number of viral RNA. In peripheral blood, 8/18 old world monkeys and 6/6 new world monkeys had viral RNA detectable on 2 dpi. After 6 days, blood samples from nearly all old world monkeys became viral RNA-positive. On 10 dpi, viral RNA was not detectable in blood samples from almost all (23/24) of experimental monkeys ( Figure 3A ). Viral load of SARS-CoV-2 was determined in tissue samples from 8 animals necropsied on 4 dpi (HHH13), 7 dpi (HHH14), 12 dpi (HHH8), 13 dpi (SXH-1, RH2, RH5) and 15 dpi (HHH3, HHH12). RT-qPCR with SARS-CoV-2 specific . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.08.031807 doi: bioRxiv preprint primers and probes was performed to quantitate copy number of viral genomic RNA. No viral RNA was detected from all tissues of two C. jacchus.
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