Author: Rose, Rebecca; Constantinides, Bede; Tapinos, Avraam; Robertson, David L; Prosperi, Mattia
Title: Challenges in the analysis of viral metagenomes Document date: 2016_8_3
ID: x3u9i1vq_12
Snippet: Paired-end reads: Reads generated from both 5 and 3 ends of the same DNA molecule. Depending on the length of the molecule and that of the reads, these pairs may or may not overlap in the middle. Read overlap graphs: A network of nodes and edges, where each edge represents a read and each vertex represents an overlap between two nodes. Reference-based alignment: Orientation/alignment of reads with respect to a specified reference sequence. Scaffo.....
Document: Paired-end reads: Reads generated from both 5 and 3 ends of the same DNA molecule. Depending on the length of the molecule and that of the reads, these pairs may or may not overlap in the middle. Read overlap graphs: A network of nodes and edges, where each edge represents a read and each vertex represents an overlap between two nodes. Reference-based alignment: Orientation/alignment of reads with respect to a specified reference sequence. Scaffolds: DNA sequences comprising contigs with gaps between them, often generated using read pairing information. Suffix array: A sorted array of all suffixes of a string, such as a DNA sequence, enabling efficient sequence comparison.
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