Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_509
Snippet: This study did not reveal significant associations between urban environment and canine immune-mediated disease. Larger studies, or studies in other geographical areas might still reveal a relationship, but the current study suggests exposures common to both rural and urban dogs merit further investigation as triggers of immune-dysregulation. Nasal lavage and oropharyngeal swabs were used to obtain resident cells from 9 healthy adult cats. The ce.....
Document: This study did not reveal significant associations between urban environment and canine immune-mediated disease. Larger studies, or studies in other geographical areas might still reveal a relationship, but the current study suggests exposures common to both rural and urban dogs merit further investigation as triggers of immune-dysregulation. Nasal lavage and oropharyngeal swabs were used to obtain resident cells from 9 healthy adult cats. The cell populations were phenotyped and enumerated using flow cytometry. After baseline samples were collected, cats were treated by intranasal and oral administration of a liposome-TLR mucosal immune stimulant (MucosImmune), and changes in immune cell populations were assessed by nasal lavage and oral swabs obtained at 6 h, 24 h and 72 h after treatment.
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