Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_603
Snippet: Lymphocytes from hyperinoculated cats proliferated significantly more in the presence of alpha-enolase compared to the other three antigens confirming the induction of a cell-mediated immune response towards alpha-enolase contained in the vaccine. Glomerular and tubular alpha-enolase expression was significantly (P < 0.05) greater at week 16 (mean score 3.37 and 1.95, respectively) compared to week 0 (0.37 and 1.01, respectively). Increased cytok.....
Document: Lymphocytes from hyperinoculated cats proliferated significantly more in the presence of alpha-enolase compared to the other three antigens confirming the induction of a cell-mediated immune response towards alpha-enolase contained in the vaccine. Glomerular and tubular alpha-enolase expression was significantly (P < 0.05) greater at week 16 (mean score 3.37 and 1.95, respectively) compared to week 0 (0.37 and 1.01, respectively). Increased cytokine concentrations over the hyperinoculation period were noted for GM-CSF (3 cats), IFN-gamma (5 cats), IL-1beta (3 cats), IL-4 (4 cats), SDF-1 (5 cats), IL-6 (4 cats), MCP-1 (3 cats), IL-13 (4 cats), IL-8 (5 cats), PDGF-BB (3 cats), RANTES (6 cats), IL-18 (3 cats), and TNF-alpha (3 cats).
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