Author: Gadsby, Naomi J.; Russell, Clark D.; McHugh, Martin P.; Mark, Harriet; Conway Morris, Andrew; Laurenson, Ian F.; Hill, Adam T.; Templeton, Kate E.
Title: Comprehensive Molecular Testing for Respiratory Pathogens in Community-Acquired Pneumonia Document date: 2016_4_1
ID: s04e6po9_21
Snippet: Bacterial load quantifications from 29 (9.1%) specimens were excluded from analysis due to the detection of partial inhibition by the IC assay. A higher bacterial load was detected by PCR in culture-positive specimens in comparison to culture-negative specimens. The mean combined bacterial load was 8.77 × 10 8 CFU/mL in culture-positive vs 7.03 × 10 7 CFU/mL in culturenegative specimens (P < .0001). Significant differences between culture-posit.....
Document: Bacterial load quantifications from 29 (9.1%) specimens were excluded from analysis due to the detection of partial inhibition by the IC assay. A higher bacterial load was detected by PCR in culture-positive specimens in comparison to culture-negative specimens. The mean combined bacterial load was 8.77 × 10 8 CFU/mL in culture-positive vs 7.03 × 10 7 CFU/mL in culturenegative specimens (P < .0001). Significant differences between culture-positive and culture-negative specimens were also observed when H. influenzae (P < .0001) and S. pneumoniae (P < .0001) were considered individually.
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