Author: Zhang, Tie-Gang; Li, Ai-Hua; Lyu, Min; Chen, Meng; Huang, Fang; Wu, Jiang
Title: Detection of respiratory viral and bacterial pathogens causing pediatric community-acquired pneumonia in Beijing using real-time PCR Document date: 2015_7_7
ID: x91sayto_25
Snippet: Respiratory syncytial virus is the leading cause of lower respiratory tract infections in the pediatric population worldwide. 19 It is responsible for an estimated 160000 deaths every year worldwide. 20 In this study, 43.9% of the CAP patients had detectable RSV, which was higher than any other pathogen. In fact the incidence of RSV was two times higher than S. pneumoniae (n ¼ 77) that was the second leading cause of CAP. Respiratory syncytial v.....
Document: Respiratory syncytial virus is the leading cause of lower respiratory tract infections in the pediatric population worldwide. 19 It is responsible for an estimated 160000 deaths every year worldwide. 20 In this study, 43.9% of the CAP patients had detectable RSV, which was higher than any other pathogen. In fact the incidence of RSV was two times higher than S. pneumoniae (n ¼ 77) that was the second leading cause of CAP. Respiratory syncytial virus was the most frequent pathogen detected in all three age groups. Rhinovirus is another frequently detected viral agent that causes adult acute respiratory infection in temperate regions. 21 Likewise, rhinovirus was also detected in this study in pediatric CAP patients. In this study two viruses that had recently been associated with CAP, human metapneumovirus and human bocavirus, were also detected using multiplex real-time PCR.
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