Author: Roberts, Christine C.
Title: Emerging infectious disease laboratory and diagnostic preparedness to accelerate vaccine development Document date: 2019_7_16
ID: v5ei8991_6
Snippet: Efforts are currently underway to alleviate the international standards issue for MERS-CoV and ZIKV. Antibody and nucleic acid standards are in development for MERS-CoV, though the additional source material is being sought. 10 In 2016, the WHO initiated a collaborative study effort for the development of ZIKV nucleic acid standards 12 and, in 2017, made available a plasma sample panel through the US Food and Drug Administration (FDA) for evaluat.....
Document: Efforts are currently underway to alleviate the international standards issue for MERS-CoV and ZIKV. Antibody and nucleic acid standards are in development for MERS-CoV, though the additional source material is being sought. 10 In 2016, the WHO initiated a collaborative study effort for the development of ZIKV nucleic acid standards 12 and, in 2017, made available a plasma sample panel through the US Food and Drug Administration (FDA) for evaluation of ZIKV immunoassays. 13 The acquisition, characterization, and standardization of relevant pathogen strains such that the strains reflect what is currently in circulation and not just a prototype strain is also of concern. For EIDs, there can be an added complication for sharing such material if the disease is caused by a select agent requiring enhanced biosafety measures.
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