Guideline for Antibiotic Use in Adults with Community-acquired Pneumonia

Lee, Mi Suk; Oh, Jee Youn; Kang, Cheol-In; Kim, Eu Suk; Park, Sunghoon; Rhee, Chin Kook; Jung, Ji Ye; Jo, Kyung-Wook; Heo, Eun Young; Park, Dong-Ah; Suh, Gee Young; Kiem, Sungmin

The CURB-65 and CRB-65 are pneumonia severity scoring systems developed using data prospectively collected from four hospitals across England, New Zealand, and the Netherlands [106] (Table 7) . The data of 80% of the 1,068 patients included in this study were used in the guideline development, and the remaining 20% were used for validating the indices. The CURB-65 assigns six scores. One point is given for satisfying each of the following conditions: C: Confusion; U: Urea >7 mmol/L (= BUN >19 mg/dL); R: Respiratory rate ≥30/min; B: Blood pressure, systolic pressure <90 mmHg or diastolic pressure ≤60 mmHg; and 65: age ≥65 years. The total resulting score ranges from 0 to 5 points. The CRB-65 is essentially the CURB-65 with the blood urea parameter requiring a blood test removed, and it assigns 0 to 4 points. The higher the CURB-65 and CRB-65 scores, the higher the mortality as shown in Table 7 . The CURB-65 and CRB-65 are reported to be on a par with one another in terms of their clinical usefulness [107] [108] [109] [110] [111] [112] [113] , and discriminatory power [110, 113] .