Author: Girardi, Erika; Chane-Woon-Ming, Béatrice; Messmer, Mélanie; Kaukinen, Pasi; Pfeffer, Sébastien
Title: Identification of RNase L-Dependent, 3'-End-Modified, Viral Small RNAs in Sindbis Virus-Infected Mammalian Cells Document date: 2013_11_19
ID: v6uc0ijw_3
Snippet: One key factor involved in IFN type I-mediated host defense is RNase L, a latent cytoplasmic endoribonuclease that is activated by 2=,5=-oligoadenylates in response to double-stranded RNA (dsRNA) sensing and that cleaves both viral and cellular RNAs (6) ......
Document: One key factor involved in IFN type I-mediated host defense is RNase L, a latent cytoplasmic endoribonuclease that is activated by 2=,5=-oligoadenylates in response to double-stranded RNA (dsRNA) sensing and that cleaves both viral and cellular RNAs (6) .
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