Selected article for: "chain reaction and molecular detection"
Author: Bjarnason, Agnar; Westin, Johan; Lindh, Magnus; Andersson, Lars-Magnus; Kristinsson, Karl G; Löve, Arthur; Baldursson, Olafur; Gottfredsson, Magnus
Title: Incidence, Etiology, and Outcomes of Community-Acquired Pneumonia: A Population-Based Study
  • Document date: 2018_2_8
    • ID: sw8ghj6q_2
    Snippet: Previous studies examining the etiology of CAP have provided widely differing results. Comparison is hampered by inherent epidemiologic differences in addition to lack of uniform inclusion criteria, study settings, and diagnostic methods. Despite rigorous attempts to identify a microbial etiology, 30%-64% of patients remain undiagnosed [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] . Studies applying molecular methods such as polymerase chain reactio.....
    Document: Previous studies examining the etiology of CAP have provided widely differing results. Comparison is hampered by inherent epidemiologic differences in addition to lack of uniform inclusion criteria, study settings, and diagnostic methods. Despite rigorous attempts to identify a microbial etiology, 30%-64% of patients remain undiagnosed [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] . Studies applying molecular methods such as polymerase chain reaction (PCR) have yielded detection rates up to 86%, but highly specific patient selection criteria designed to optimize sample collection make comparisons difficult [13] . There is a dearth of population-based observational studies with high inclusion rates examining pneumonia incidence and etiology while avoiding overly selective inclusion criteria and applying modern diagnostic methods.

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