Selected article for: "RdRp RNA dependent RNA polymerase and RNA polymerase"
Author: Mohamed, Fakry F.; Ktob, Gamelat K.F.; Ismaeil, Mohamed E.A.; Ali, Ahmed A.H.; Goyal, Sagar M.
Title: Phylogeny of bovine norovirus in Egypt based on VP2 gene
  • Document date: 2018_4_13
    • ID: rah5p1y4_3
    Snippet: The reverse transcription-polymerase chain reaction (RT-PCR) is commonly used for norovirus detection. The RT-PCR usually targets the RNA dependent RNA polymerase (BNoV-RdRp) gene because it contains highly conserved regions. For phylogenetic classification, RT-PCR targets the BNoV-VP1 gene. Recently, several recombination events have been detected at the ORF1/ORF2 junction, thus imposing a new genotyping strategy within the Norovirus genus. It w.....
    Document: The reverse transcription-polymerase chain reaction (RT-PCR) is commonly used for norovirus detection. The RT-PCR usually targets the RNA dependent RNA polymerase (BNoV-RdRp) gene because it contains highly conserved regions. For phylogenetic classification, RT-PCR targets the BNoV-VP1 gene. Recently, several recombination events have been detected at the ORF1/ORF2 junction, thus imposing a new genotyping strategy within the Norovirus genus. It was reported that GIII.P1/GIII.2 had a GIII.1-related RdRp and a GIII.2-related VP1 while GIII.P2/GIII.1 had a GIII.2-related RdRp and a GIII.1-related VP1. This indicates that both BNoV-RdRp and BNoV-VP1 should be determined for phylogenetic purposes [13] .

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