Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans

Comparison of the sequence of the 3' untranslated region of murine Man II with the GenBank database (version 67.0) revealed that the extended 3'-untranslated region contains a Arrows indicate the positions of the major and minor message species in rat tissues. The blot in lane 1 was exposed to x-ray film for 8 d at -70°C. The gel in the remaining lanes was exposed for 2 d at 70°C. single interrupted copy of a mouse Bl repetitive sequence (data not shown), the mouse equivalent of the human Alu consensus sequence (20, 48) .