Measurement of serum 7a-hydroxy-4-cholesten-3-one as a marker of bile acid malabsorption in dogs with chronic diarrhoea: a pilot study

Kent, A. C. C.; Cross, G.; Taylor, D. R.; Sherwood, R. A.; Watson, P. J.

The remaining 14 clinical cases were treated with a variety of medications, depending on diagnosis and had a range of outcomes. The two cases of antibiotic-responsive enteropathy, two cases of diet-responsive enteropathy, two case of suspected enteric coronavirus and two case of exocrine pancreatic insufficiency were all treated appropriately for those conditions with an excellent response. The eight cases with idiopathic inflammatory bowel disease were treated with a number of medications, including prednisolone alone (five cases), prednisolone with azathioprine (one case), prednisolone with chlorambucil (one case) and prednisolone with ciclosporin (one case). Seven of these eight cases responded well to treatment with good long-term control of clinical signs; one case deteriorated despite therapy resulting in eventual euthanasia. This dog had a low serum C4 level (25.12 nmol/l).