Author: Choi, Kang-Seuk
Title: Newcastle disease virus vectored vaccines as bivalent or antigen delivery vaccines Document date: 2017_7_26
ID: vk59ghjm_15
Snippet: To generate a live attenuated vaccine with improved efficacy, a NDV-vectored rabies vaccine (rL-RVG) containing the RV G glycoprotein was developed [24] . Animal experiments demonstrated that rL-RVG induced production of RV neutralizing antibodies at levels comparable with those induced by a live attenuated RV vaccine (ERA strain) and provided complete protection against challenge with a potentially fatal virus strain (GX/09) for more than 1 year.....
Document: To generate a live attenuated vaccine with improved efficacy, a NDV-vectored rabies vaccine (rL-RVG) containing the RV G glycoprotein was developed [24] . Animal experiments demonstrated that rL-RVG induced production of RV neutralizing antibodies at levels comparable with those induced by a live attenuated RV vaccine (ERA strain) and provided complete protection against challenge with a potentially fatal virus strain (GX/09) for more than 1 year [24] .
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