Author: Chang, Stewart T.; Sova, Pavel; Peng, Xinxia; Weiss, Jeffrey; Law, G. Lynn; Palermo, Robert E.; Katze, Michael G.
Title: Next-Generation Sequencing Reveals HIV-1-Mediated Suppression of T Cell Activation and RNA Processing and Regulation of Noncoding RNA Expression in a CD4(+) T Cell Line Document date: 2011_9_20
ID: zyzgk2z3_30
Snippet: In conclusion, using NGS, we have reported a number of unique findings in HIV-infected cells: the direct measurement of viral and host RNA, the detection of small changes in the abundance of mRNA transcripts, the identification of novel viral RNA splice events, and the assay of multiple forms of noncoding RNAs, including insights into the regulation of microRNAs. These observations give additional insights into the panoply of changes that occur i.....
Document: In conclusion, using NGS, we have reported a number of unique findings in HIV-infected cells: the direct measurement of viral and host RNA, the detection of small changes in the abundance of mRNA transcripts, the identification of novel viral RNA splice events, and the assay of multiple forms of noncoding RNAs, including insights into the regulation of microRNAs. These observations give additional insights into the panoply of changes that occur in host cells infected with HIV and provide the groundwork for using new sequencing technologies in future studies investigating the host response to viral infection.
Search related documents:
Co phrase search for related documents- additional insight and host response: 1
- direct measurement and host cell: 1
- direct measurement and host response: 1
- future study and host cell: 1, 2, 3, 4, 5, 6
- future study and host response: 1, 2, 3, 4, 5
- groundwork provide and host cell: 1, 2
- groundwork provide and host response: 1, 2
- HIV infect and host cell: 1, 2
- host cell and mRNA transcript: 1, 2, 3
Co phrase search for related documents, hyperlinks ordered by date