Author: Matsuo, Keisuke; Ishiguro, Takashi; Najama, Takatomo; Shimizu, Yoshihiko; Kobayashi, Yasuhito; Mutou, Makoto
Title: Nivolumab-induced Myocarditis Successfully Treated with Corticosteroid Therapy: A Case Report and Review of the Literature Document date: 2019_5_22
ID: y2n9z5sd_5
Snippet: We initially suspected acute myocardial infarction, and a Swan-Ganz catheter was inserted to assist in management in the intensive care unit. The pulmonary artery pressure [systolic/diastolic (mean)] was 28/19 (23) mmHg. Emergency coronary angiography was performed, but no significant stenosis of the coronary arteries was found. We also performed various CMR examinations (Fig. 2) . Cine images showed diffuse moderately reduced wall motion abnorma.....
Document: We initially suspected acute myocardial infarction, and a Swan-Ganz catheter was inserted to assist in management in the intensive care unit. The pulmonary artery pressure [systolic/diastolic (mean)] was 28/19 (23) mmHg. Emergency coronary angiography was performed, but no significant stenosis of the coronary arteries was found. We also performed various CMR examinations (Fig. 2) . Cine images showed diffuse moderately reduced wall motion abnormality with mild wall hypertrophy, and T2-weighted short-tau inversion recovery (STIR) black-blood (BB) (T2w-STIR-BB) imaging showed diffuse high signal intensity (SI) equal to or greater than the spleen SI. Early gadolinium-enhanced (EGE) imaging showed diffuse hyper-enhancement of the myocardium, and late gadolinium-enhanced imaging showed diffuse patchy enhancement. Given the above findings, we diagnosed him with myocarditis with diffuse myocardial edema.
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