Selected article for: "cell culture and different cell"
Author: Parvez, Mohammad K.; Tabish Rehman, Md.; Alam, Perwez; Al-Dosari, Mohammed S.; Alqasoumi, Saleh I.; Alajmi, Mohammed F.
Title: Plant-derived antiviral drugs as novel hepatitis B virus inhibitors: Cell culture and molecular docking study
  • Document date: 2018_12_26
    • ID: xibqsjib_4
    Snippet: The HBV-reporter cell line, HepG2.2.15 is one of the established systems for preliminary screening of anti-HBV drugs in vitro. The in silico molecular docking tool enables to assess the binding ability of a ligand to protein active-site as well as to compare the binding modes of different ligands to the active site-pocket (Leach, 2001) . Therefore, in this study, we evaluated the novel anti-HBV activity as well as delineated mechanism of action o.....
    Document: The HBV-reporter cell line, HepG2.2.15 is one of the established systems for preliminary screening of anti-HBV drugs in vitro. The in silico molecular docking tool enables to assess the binding ability of a ligand to protein active-site as well as to compare the binding modes of different ligands to the active site-pocket (Leach, 2001) . Therefore, in this study, we evaluated the novel anti-HBV activity as well as delineated mechanism of action of selected plantderived compounds of different classes, using cell culture and molecular docking methods.

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