Author: Parvez, Mohammad K.; Tabish Rehman, Md.; Alam, Perwez; Al-Dosari, Mohammed S.; Alqasoumi, Saleh I.; Alajmi, Mohammed F.
Title: Plant-derived antiviral drugs as novel hepatitis B virus inhibitors: Cell culture and molecular docking study Document date: 2018_12_26
ID: xibqsjib_71
Snippet: Hespiridin is a flavonoid with very limited knowledge of antiviral activities. A water-soluble derivative of hesperidin, glucosyl hesperidin has been reported to have in vitro inhibitory activities against human and avian influenza A viruses (Saha et al., 2009 ). Our present data demonstrated the novel anti-HBV potential of hesperidin. In molecular docking, hesperidin formed bonds with Glu39, Ser40, Ser85, Ser117 and His156 where the hesperidin-P.....
Document: Hespiridin is a flavonoid with very limited knowledge of antiviral activities. A water-soluble derivative of hesperidin, glucosyl hesperidin has been reported to have in vitro inhibitory activities against human and avian influenza A viruses (Saha et al., 2009 ). Our present data demonstrated the novel anti-HBV potential of hesperidin. In molecular docking, hesperidin formed bonds with Glu39, Ser40, Ser85, Ser117 and His156 where the hesperidin-Pol complex had a free energy of À9.3 kcal/mol.
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