Author: Chan, Joseph M.; Rabadan, Raul
Title: Quantifying Pathogen Surveillance Using Temporal Genomic Data Document date: 2013_1_29
ID: u2t1x89m_1
Snippet: D espite many therapeutic and epidemiological advances, infectious diseases-the number one cause of death among children-remain directly responsible for roughly 15 million (Ͼ25%) of the annual deaths that occur worldwide (1) . Of particular concern are emerging infections (EIs) that include novel entities like HIV/AIDS and severe acute respiratory syndrome and previously existing but rapidly spreading diseases like cholera and the plague (2, 3) .....
Document: D espite many therapeutic and epidemiological advances, infectious diseases-the number one cause of death among children-remain directly responsible for roughly 15 million (Ͼ25%) of the annual deaths that occur worldwide (1) . Of particular concern are emerging infections (EIs) that include novel entities like HIV/AIDS and severe acute respiratory syndrome and previously existing but rapidly spreading diseases like cholera and the plague (2, 3) . Zoonosis is a rich source of such EI transmission into human hosts (4) , suggesting that pathogen surveillance of animals, as well as humans, is an important method of early detection of potential outbreaks and of capturing the entire biodiversity of a pathogen population at any given place and time.
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