Author: Chan, Joseph M.; Rabadan, Raul
Title: Quantifying Pathogen Surveillance Using Temporal Genomic Data Document date: 2013_1_29
ID: u2t1x89m_31
Snippet: Compared to human H3N2 and H1N1 surveillance, human and avian H5N1 influenza virus surveillance is lower at q2 coefficients of 0.838 and 0.923, respectively. Although these the q2 coefficients are already high, the difference in the q2 coefficient may suggest that there are strains of H5N1 circulating in bird and even possibly human hosts that remain undetected. Given the recent discovery of molecular determinants that enable ferret-to-ferret tra.....
Document: Compared to human H3N2 and H1N1 surveillance, human and avian H5N1 influenza virus surveillance is lower at q2 coefficients of 0.838 and 0.923, respectively. Although these the q2 coefficients are already high, the difference in the q2 coefficient may suggest that there are strains of H5N1 circulating in bird and even possibly human hosts that remain undetected. Given the recent discovery of molecular determinants that enable ferret-to-ferret transmission of H5N1 virus (10) , it is all the more important to increase viral isolation to match or exceed the levels of human H3N2 and H1N1 surveillance.
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