Research Communications of the 24th ECVIM-CA Congress

Financial support from Dechra pharmaceuticals. The prognosis of canine adrenocortical insufficiency is generally regarded to be excellent. However, there is paucity of sur-vival analyses in the literature. The aim of the present study was to evaluate the survival of dogs with the diagnosis adrenocortical insufficiency based on data from a cohort of 525, 028 Swedish client-owned dogs insured in one insurance company (Agria Pet Insurance, Stockholm, Sweden) during the time period 1995-2006. Dogs were identified by search for insurance claims with the register code for adrenocortical insufficiency. Dogs were excluded from analysis if they had a previous history of hypercortisolism, and if they were born before begin of the study period. Kaplan-Meier survival analysis was performed. Dogs were regarded as censored when the registered cause of death was other than adrenocortical insufficiency or hypercortisolism that was registered after the first claim for adrenocortical insufficiency. Data from 297 dogs was included. One hundred twenty-four dogs were registered to be dead. In 81 dogs the cause of death was related to the adrenocortical insufficiency. The 1-year estimated survival-rate was 81% (95% CI, 76-86%). The 3-year estimated survival-rate was 69% (95% CI, 63-76%). The 5-year estimated survival-rate was 59% (95% CI, 51-68%). Twelve dogs (4.0%) were still alive after 7 years. In conclusion, the long-term survival of dogs with adrenocortical insufficiency was reasonably good. However, the diseases-related mortality was higher than expected, and occurred mainly during the first years after diagnosis.