Selected article for: "cut value and response rate"
Title: Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017
  • Document date: 2017_11_7
    • ID: roslkxeq_338
    Snippet: The median value of pretreatment plasma D-dimer was 0.4 lg/ mL (range: 0.1-14.3 lg/mL). The optimal cut-off value of D-dimer based on Progressive Free Interval (PFI) was 0.5 lg/mL (HR: 2.22, P = 0.014). A D-dimer level >0.5 lg/mL was significantly associated with inferior PFI (54 vs. 104 days, P = 0.01). Dogs with a D-dimer level >0.5 lg/mL had a significantly worse survival than those with a D-dimer level ≤ 0.5 lg/mL (OS: 93 vs. 177 days, P = .....
    Document: The median value of pretreatment plasma D-dimer was 0.4 lg/ mL (range: 0.1-14.3 lg/mL). The optimal cut-off value of D-dimer based on Progressive Free Interval (PFI) was 0.5 lg/mL (HR: 2.22, P = 0.014). A D-dimer level >0.5 lg/mL was significantly associated with inferior PFI (54 vs. 104 days, P = 0.01). Dogs with a D-dimer level >0.5 lg/mL had a significantly worse survival than those with a D-dimer level ≤ 0.5 lg/mL (OS: 93 vs. 177 days, P = 0.01). High D-dimer levels were not correlated with na€ ıve versus relapsed lymphoma, B versus T lymphoma, clinical stage, substage and morphotype. High D-dimer levels remained an independent predictor for treatment received (etoposide phosphate vs. F14512, P = 0.97). There was no difference in response rate and PFI between dogs treated with F-14512 versus etoposide phosphate (ORR: 44% vs. 45%, P = 0.92; PFI: 86 vs. 87.5 days, P = 0.34 respectively).

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