Selected article for: "ACTH concentration and plasma ACTH concentration"

Title: Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017
  • Document date: 2017_11_7
  • ID: roslkxeq_559
    Snippet: The clinical records of 202 dogs with spontaneous hypercortisolism, referred to the authors' institution, were reviewed. Diagnosis was based on physical and biochemical changes suggestive of hypercortisolism and confirmed by endocrine function tests. Endocrine tests revealing dexamethasone resistance in combination with an endogenous plasma ACTH concentration <40 ng/mL was interpreted as functional AT. In all dogs, pre-and postcontrast CT of both.....
    Document: The clinical records of 202 dogs with spontaneous hypercortisolism, referred to the authors' institution, were reviewed. Diagnosis was based on physical and biochemical changes suggestive of hypercortisolism and confirmed by endocrine function tests. Endocrine tests revealing dexamethasone resistance in combination with an endogenous plasma ACTH concentration <40 ng/mL was interpreted as functional AT. In all dogs, pre-and postcontrast CT of both the pituitary gland and the adrenal glands was performed. A pituitary/brain (P/B) ratio >0.31 was interpreted as enlarged, consistent with a PT. Heterogeneous adrenal structure, asymmetric shape, and adrenal width >15 mm were consistent with an AT. Adrenal expansion into blood vessels greatly supported the diagnosis of an AT.

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