Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017

Bloodwork revealed hypocobalaminemia (138 pmol/L, ref. 200-408) and hypofolatemia (6.7 nmol/L, ref. 12-30) consistent with diffuse small intestinal disease. Hematology and biochemistry were unremarkable. A gastrointestinal endoscopy documented multiple small masses in the rectum and the colon (>50 in total). These masses were present on the last 20 cm of the large intestine. The mucosa around the masses appeared irregular and swollen. The ileum appeared mildly irregular. Histopathology of the masses identified a population of large cells with granular cytoplasm multifocally expanding the lamina propria between the glands, consistent with granular cell tumors. There was also a mild aggregation of lymphocytes, plasma cells and sparse eosinophils in the colic mucosa between the masses. There was minimal lacteal dilation in the ileum, with no evidence of inflammation. Additional stains did not yield significant information. Bacterial and fungal cultures of colic biopsies were negative.