RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS

Twenty‐four dogs diagnosed with CE were enrolled, and left‐over biopsy samples from the duodenum were evaluated for LRG expression, with both quantitative polymerase chain reaction (qPCR) and immunohistochemistry. As a control, cryopreserved biopsy samples from the duodenum of ten healthy control dogs with no clinical signs of gastrointestinal disease were used. The Wilcoxon rank sum test was used to compare the LRG mRNA expression in the two groups. The relationship between LRG mRNA expression and the canine chronic enteropathy clinical activity index (CCECAI) or a histopathological score graded according to the guidelines of the WSAVA International Gastrointestinal Standardization Group was evaluated with Spearman's rank correlation coefficient. Statistical significance was defined as P < 0.05.