Selected article for: "cap structure and enzymatic activity"

Author: Byszewska, Magdalena; Smietanski, Miroslaw; Purta, Elzbieta; Bujnicki, Janusz M
Title: RNA methyltransferases involved in 5' cap biosynthesis
  • Document date: 2015_1_27
  • ID: sz2531mv_6
    Snippet: Throughout the article, we follow the nomenclature of cap modifying enzymes and their products commonly used in the literature. We use terms "capX methylation" and "capX methyltransferase" (where X is a number) to refer to some enzymatic activity or its product at a particular position X. On the other hand, the term "capX structure" is used to refer to a fully modified cap structure. For instance "cap2 structure" indicates a cap methylated on the.....
    Document: Throughout the article, we follow the nomenclature of cap modifying enzymes and their products commonly used in the literature. We use terms "capX methylation" and "capX methyltransferase" (where X is a number) to refer to some enzymatic activity or its product at a particular position X. On the other hand, the term "capX structure" is used to refer to a fully modified cap structure. For instance "cap2 structure" indicates a cap methylated on the inverted guanosine and the first 2 ribose sugars in the nucleotide sequence; i.e., m 7 GpppN 1 mN 2 m. It should be emphasized that some of the cap methyltranserases discussed here have not yet been fully characterized and it cannot be ruled out that they act at multiple positions.

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