Author: Bhuiyan, Mejbah Uddin; Snelling, Thomas L; West, Rachel; Lang, Jurissa; Rahman, Tasmina; Borland, Meredith L; Thornton, Ruth; Kirkham, Lea-Ann; Sikazwe, Chisha; Martin, Andrew C; Richmond, Peter C; Smith, David W; Jaffe, Adam; Blyth, Christopher C
Title: Role of viral and bacterial pathogens in causing pneumonia among Western Australian children: a case–control study protocol Document date: 2018_3_16
ID: w3rxdaii_36
Snippet: A total of 250 cases and 250 controls will be enrolled. The power of the study to detect a significantly higher rate of pathogen detection among cases versus controls is dependent on the frequency of pathogen detection in healthy controls. Using data from previously published literature among pneumonia cases and healthy controls [10, 48] , it was estimated that a sample size of 250 pneumonia cases and 250 healthy controls would provide 80% power .....
Document: A total of 250 cases and 250 controls will be enrolled. The power of the study to detect a significantly higher rate of pathogen detection among cases versus controls is dependent on the frequency of pathogen detection in healthy controls. Using data from previously published literature among pneumonia cases and healthy controls [10, 48] , it was estimated that a sample size of 250 pneumonia cases and 250 healthy controls would provide 80% power to identify a significant excess in pathogen detection (lower bound of 95% confidence interval > 1) among cases compared to controls, ranging from at least 3% (for influenza) to 15% (for rhinovirus).
Search related documents:
Co phrase search for related documents- confidence interval and control compare case: 1, 2, 3, 4
- confidence interval and healthy control: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- confidence interval and pathogen detection: 1, 2, 3, 4, 5, 6, 7, 8
- confidence interval and pneumonia case: 1, 2, 3, 4, 5, 6
- confidence interval and sample size: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- confidence interval and significant excess: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- confidence interval and significantly high rate: 1, 2, 3, 4
- confidence interval and study power: 1, 2, 3, 4, 5, 6, 7, 8
- control compare and healthy control: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- control compare and sample size: 1, 2, 3, 4
- healthy control and pneumonia case: 1
- healthy control and sample size: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- healthy control and study power: 1
- pathogen detection and pneumonia case: 1, 2
- pathogen detection and sample size: 1, 2, 3, 4
- pathogen detection and significant excess: 1
- pathogen detection and study power: 1, 2, 3
- pneumonia case and sample size: 1, 2
- sample size and significant excess: 1, 2
Co phrase search for related documents, hyperlinks ordered by date