Author: Qin, Jian; Jones, Robert C.; Ramakrishnan, Ramesh
Title: Studying copy number variations using a nanofluidic platform Document date: 2008_8_18
ID: prsvv6l9_15
Snippet: There are 765 chambers in each of the 12 panels in a digital array. When single DNA molecules are randomly partitioned into these chambers, it is possible that multiple molecules could partition into the same chamber. As a result there could be more molecules in each panel than positive chambers. The true number of molecules per chamber can be estimated using a simple Poisson distribution equation as described by Sindelka et al. (15) . We have de.....
Document: There are 765 chambers in each of the 12 panels in a digital array. When single DNA molecules are randomly partitioned into these chambers, it is possible that multiple molecules could partition into the same chamber. As a result there could be more molecules in each panel than positive chambers. The true number of molecules per chamber can be estimated using a simple Poisson distribution equation as described by Sindelka et al. (15) . We have developed a more robust computational algorithm to analyze CNV data obtained from the digital array. This algorithm has been integrated into the Digital PCR Analysis software and is detailed in (19) .
Search related documents:
Co phrase search for related documents- digital array and PCR Analysis software: 1, 2
- Digital PCR Analysis software and PCR Analysis software: 1, 2
- dna molecule and multiple molecule: 1, 2
- dna molecule and single dna molecule: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
Co phrase search for related documents, hyperlinks ordered by date